The complexity of cellular behaviors go beyond the sequence of the genome. DNA methylation states, histone modifications, chromatin accessibility and the 3-dimensional spatial arrangements of chromatin are important factors working in concert to define global gene expression pattern of every single cell. Understanding these critical aspects will grant us a better understanding of cellular mechanisms.

In order to consistently generate high-quality data, optimized and standardized protocols are necessary. Below are links to some of the protocols used by the HKUST Center of Epigenomics and to the data deposited to IHEC.